Chemistry and Molecular Aspects of Drug Design and Action by E. A. Rekka,P. N. Kourounakis PDF

By E. A. Rekka,P. N. Kourounakis

An ever-increasing call for for greater medicinal drugs, increased security criteria, and monetary concerns have all resulted in a dramatic paradigm shift within the means that medicinal drugs are being came upon and constructed. referred to as rational drug layout, this modern procedure is outlined via 3 major steps: the invention of lead compounds, surgical manipulation to boost pharmacophores, and additional optimization to supply the simplest compounds.

Chemistry and Molecular elements of Drug layout and Action brings jointly a magnificent number of world-renowned pharmacochemistry scientists who're at the moment defining the emergence of rational drug layout. providing perception from their very own really expert examine, those pioneers spotlight the range of techniques being hired during this box, together with those who begin by way of contemplating both molecular mechanisms of drug motion, or the metabolizing enzyme motion taking place within the constitution of a drug molecule. one other process they discover is person who begins from the pathobiochemistry and pathophysiology of goal illnesses. moreover, the booklet additionally considers drug improvement that uses already built compounds saved in facts banks.

Divided into 5 components, every one devoted to a number of features of the classical medicinal chemistry procedure, the textual content makes it effortless for readers to target a box of particular curiosity.

  • Chemical, Biochemical, and organic points of Pathophysiological Conditions
  • Classical Medicinal Chemistry
  • Drug layout, Chemical and Molecular elements of Drug Action
  • Drug Xenobiotic Metabolism
  • Physical natural and Theoretical Medicinal Chemistry
  • While each one part will be studied independently, the mixed fabric during this quantity presents the main complete review to be had on rational drug layout. This paintings is a useful source either for these coming into the sector, in addition to these researchers trying to construct on present progress.

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